haidut
Member
It's just one study with 22 people but the findings resonate quite well with the health profiles I have seen on long distance runners - i.e. developing asthma, lung fibrosis and enlarged heart. Those are chronic problems, and the study did not look if the kidney failure fully recovered after day 2 or became chronic in some people. But assuming every marathon run can cause even temporary kidney failure for 80%+ of runners then it is something a person should probably not be doing, either short- or long-term.
I would definitely like to see this replicated with a much bigger group, which should be easy to do given how many large scale, general population marathons occur in the US every year.
http://www.ajkd.org/article/S0272-6386(17)30536-X/fulltext
"...22 marathon runners were included. Mean age was 44 years and 41% were men. 82% of runners developed an increase in creatinine level equivalent to AKIN-defined AKI stages 1 and 2. 73% had microscopy diagnoses of tubular injury. Serum creatinine, urine albumin, and injury and repair biomarker levels peaked on day 1 and were significantly elevated compared to day 0 and day 2. Serum creatine kinase levels continued to significantly increase from day 0 to day 2."
I would definitely like to see this replicated with a much bigger group, which should be easy to do given how many large scale, general population marathons occur in the US every year.
http://www.ajkd.org/article/S0272-6386(17)30536-X/fulltext
"...22 marathon runners were included. Mean age was 44 years and 41% were men. 82% of runners developed an increase in creatinine level equivalent to AKIN-defined AKI stages 1 and 2. 73% had microscopy diagnoses of tubular injury. Serum creatinine, urine albumin, and injury and repair biomarker levels peaked on day 1 and were significantly elevated compared to day 0 and day 2. Serum creatine kinase levels continued to significantly increase from day 0 to day 2."