Life-Extension Drug LOY-001 For Dogs Over 40lbs Is Probably A Few Years Away

[Clyde]

A New Drug That Could Extend Dogs' Lives Inches Closer to Approval

For the first time, the FDA has indicated a willingness to endorse a longevity drug

www.smithsonianmag.com

...LOY-001, is an injection-based treatment that targets a growth and metabolism hormone called IGF-1. This hormone seems to be size-related—it appears in higher levels in larger dogs and in lower levels in smaller dogs.

LOY-001 is designed for healthy dogs over the age of seven and above 40 pounds, and it would be administered every three to six months by a veterinarian. The company is also simultaneously working to develop a daily pill called LOY-003.

I would have posted a chemical description but don't see it online yet.

 

[Clyde]

I still can't find the chemicals to post them. Maybe they're old chemicals that have been modified or repurposed. (LOY-003 is being developed to be taken orally while LOY-001 is injectable.)

IMO that it's being trialed for dogs doesn't mean it has no human application. Sometimes it seems like pets get more rational medical care than people do.

Haidut had some good posts on igf-1 and longevity.

Lower Growth Hormone (hGH) And IGF-1 Levels In Men Extends Lifespan

The study is important because it was done on humans and confirms a lot of what Ray has written about the dangers of pituitary hormones, including hGH. Combined with the well-known link between hGH and cancer I am not sure how sane the doctor advising all the athletes juicing with hGH are. The...

raypeatforum.com

"Anti-aging" Hormone (hGH) May Actually Shorten Life

The duo of hGH/IGF-1 does not need an introduction. Hardly a day passes without some ad on TV promoting the latest and greatest product that "naturally boosts" either hGH or IGF-1 levels. The two hormones have an almost perfect correlation - each one inducing the endogenous synthesis of the...

raypeatforum.com

Growth Hormone (GH) Accelerates Aging

Animal study, but the effects have been observed in humans as well. One of the suspected reasons is that GH chronically elevates cortisol, among other things Peat wrote about as well. http://www.ncbi.nlm.nih.gov/pubmed/14583653

raypeatforum.com

 

[tasfarelel]

Not meant to convince anyone - but, a IGF-1 inhibitor will very likely do nothing to extend lifespan of any mammal. Especially not healthy life span.