bruschi11
Member
- Joined
- Dec 20, 2016
- Messages
- 687
Deep thinking…..
B2, when getting to FAD, raises glycine. B2 without getting to FAD raises cysteine/histidine through fmn.
Manganese/carnosine raises histidine.
Zinc raises cysteine and possibly glutamate at times.
B12/ b1 raise threonine.
The biggest thing is once b6 is activated, you gotta have places for cysteine to go. Histidine AND threonine are HUGE amino cysteine movers. And thing is… they move cysteine to GREAT places.
Cysteine to sulfur via histidine. And cysteine to Krebs cycle via threonine.
But the big one. Glycine. GLYCINE uses cysteine for glutathione. But b2 needs to get to fad to produce glycine. B2 getting stuck at fmn and not getting to fad is a disaster raising cysteine/histidine even more without glycine!!
So in reality the goal here. Cysteine production and metabolism needs the production of all 3 of histidine threonine glycine.
Glycine comes before threonine cuz threonine needs nadph. Glycine/ chloride / potassium is step 1 to nadph.
Histidine comes before threonine too. As many will tell you Mn comes before b1.
Fascinating really. I’m just sooo sick.
B2, when getting to FAD, raises glycine. B2 without getting to FAD raises cysteine/histidine through fmn.
Manganese/carnosine raises histidine.
Zinc raises cysteine and possibly glutamate at times.
B12/ b1 raise threonine.
The biggest thing is once b6 is activated, you gotta have places for cysteine to go. Histidine AND threonine are HUGE amino cysteine movers. And thing is… they move cysteine to GREAT places.
Cysteine to sulfur via histidine. And cysteine to Krebs cycle via threonine.
But the big one. Glycine. GLYCINE uses cysteine for glutathione. But b2 needs to get to fad to produce glycine. B2 getting stuck at fmn and not getting to fad is a disaster raising cysteine/histidine even more without glycine!!
So in reality the goal here. Cysteine production and metabolism needs the production of all 3 of histidine threonine glycine.
Glycine comes before threonine cuz threonine needs nadph. Glycine/ chloride / potassium is step 1 to nadph.
Histidine comes before threonine too. As many will tell you Mn comes before b1.
Fascinating really. I’m just sooo sick.
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