Finally Cured From Post Finasteride Syndrome

[Santosh]

Did you have any sides during or after mtren? You were running a test base in addition to the mtren? I’ve read 19-nors are suppressive for a long while after cessation. Are you or did you run a trt-level dose of test for a while after you stopped? Thank you.

Few mg of test before, while, after.
No sides whatsoever and no suppression.

19nor suppression is another broscience myth that everyone believes but no one tests for themselves.

 

[VladSokolov]

Just wanted to update to pass ideas. I did carnivore diet for 2 weeks then one day of water fast with a bowel prep (the one they use to clear out your colon before colonoscopy). Also took iodine on and off during this time. This was in preparation for FMT. That night I also took proviron 25mg. The next morning my junk looked almost normal and felt almost normal. I even had libido. After I did the FMT I feel like I crashed and now feel worse than before. I’m waiting it out because it can take 2 months for your microbiome to reflect that of FMT. I wonder if I didn’t do the FMT if those benefits would have stayed. I’m also on transdermal TRT and hcg for past 1-2 months.

I wonder if by removing all food particles and bacteria in my gut inflammation dropped so low that proviron and TRT were actually able to work. Then with the introduction of many bacteria my gut inflammation increased and then those activated genes or pathways were shut down again.

I plan on repeating carnivore for 2 weeks then water fast with a bowel prep while on TRT, hcg, proviron to see if I can replicate those results.

 

[maillol]

Please don't follow your opinion then, you're wrong.

Estrogen is needed to sensitize androgen receptors. Once it's there, it's there.

Your androgen receptors are desensitized because they have been deprived from estrogens for so long.

You just need to add the most potent androgen known to man to further sensitize the androgen receptor, not to do anything to the estrogen receptor.

In this case do you think that exogenous estradiol would also resensitise androgen receptors?

 

[Aromasin]

In this case do you think that exogenous estradiol would also resensitise androgen receptors?

It didn’t help in my experience. I will update once I try mtren.

 

[maillol]

It didn’t help in my experience. I will update once I try mtren.

Interesting, how much did you try? I also crashed from aromasin use around the same time as you and a couple of 2mg doses of E2 pretty much reset me. This is very modest and I may well benefit from more but high estrogen is still a concern for obvious reasons. You might find this paper interesting -

Transient administration of estradiol-17.8 establishes an autoregulatory loop permanently inducing estrogen receptor mRNA

 

[mey]

It didn’t help in my experience. I will update once I try mtren.

Where do you get mtren ?

 

[Aromasin]

Interesting, how much did you try? I also crashed from aromasin use around the same time as you and a couple of 2mg doses of E2 pretty much reset me. This is very modest and I may well benefit from more but high estrogen is still a concern for obvious reasons. You might find this paper interesting -

Transient administration of estradiol-17.8 establishes an autoregulatory loop permanently inducing estrogen receptor mRNA

I’ve tried anywhere from 0.25mg -> 6mg per day of oral estradiol valerate. Glad to hear estrogen helped you. Did you take estradiol via intramuscular injection or orally? With high serum estrogen levels I only notice bloating and some anxiety. A bit of appetite suppression. No sensitivity at the nipple or anything like that.

 

[maillol]

I’ve tried anywhere from 0.25mg -> 6mg per day of oral estradiol valerate. Glad to hear estrogen helped you. Did you take estradiol via intramuscular injection or orally? With high serum estrogen levels I only notice bloating and some anxiety. A bit of appetite suppression. No sensitivity at the nipple or anything like that.

In total I only ever took 50mg of aromasin, I imagine you took much more if you were doing it during trt.

I took the estradiol orally. No nipple sensitivity for me either, whereas I have felt it from raw test. Interesting isn't it. My theory on that is because estradiol predominantly activates ERa whereas it seems that ERb is the one responsible for gyno.

Have you got MTREN ordered? Keep us updated.

 

[Aromasin]

Where do you get mtren ?

I DM’d you.

 

[Aromasin]

In total I only ever took 50mg of aromasin, I imagine you took much more if you were doing it during trt.

I took the estradiol orally. No nipple sensitivity for me either, whereas I have felt it from raw test. Interesting isn't it. My theory on that is because estradiol predominantly activates ERa whereas it seems that ERb is the one responsible for gyno.

Have you got MTREN ordered? Keep us updated.

Yes, I used to take 25mg per day Aromasin. It didn’t take long to feel the effects of that. Maybe 2 months max. Interesting, when you say raw test, are you talking about test no ester? I have it in my possession, I just haven’t pulled the trigger yet. I’ll update when I do.

 

[maillol]

Yes, I used to take 25mg per day Aromasin. It didn’t take long to feel the effects of that. Maybe 2 months max. Interesting, when you say raw test, are you talking about test no ester? I have it in my possession, I just haven’t pulled the trigger yet. I’ll update when I do.

Yeah no ester. Quite powerful but only for a few hours because of the short half life. Felt good pre gym but I never used it for long because it was bad for my sleep.

 

[Mister]

Update from a guy on HCG:

This is his second HCG cycle and doing it for 80 days. His previous one was 6 months at 250IU EOD. Now 500IU every 4th day.

Also this is interesting about various hdaci's and methylators:

Even Alchohol is a hypermethylator.

 

[FinVictim]

Interesting update. I have been on 300-400IU eod for 1.5 years without improvements (early 2021 - late 2022), but I might have to try again some time.

Do you have a link to the mentioned publication on HDAC-inhibition?

 

[TTorque]

Nothing really new. But more exposure about over/under regulated genes.
Search for Sources of Major PFS Symptoms Pinpoints 186 Brain Genes – The Post-Finasteride Syndrome Foundation

It's shooting from the hip. But tons of anabolics and a stack of transcriptional "modifiers", is this the new "protocol"?
There was a comment on valp + 10g of Berberine, while on a clean diet/low stress environment restored functionality after a decade.

 

[Mister]

Interesting update. I have been on 300-400IU eod for 1.5 years without improvements (early 2021 - late 2022), but I might have to try again some time.

Do you have a link to the mentioned publication on HDAC-inhibition?

Yes I tried HCG too now but didn't help, still one of the best and "safest" regimens you can try first imo.

And the image was posted in the whatsapp group, I assume this is from a paywalled article.

There was a comment on valp + 10g of Berberine, while on a clean diet/low stress environment restored functionality after a decade.

Oh interesting, do you have a link to this recovery?

 

[Mister]

New PFS update video from Russo, will be his last one he said.



Nothing new besides him and Jasper confirming to be practically 100% recovered and Russo addressing the drama of him charging so much for his calls.

Also they confirmed they did not use testosterone when they did their DHB and VPA regimen, they tried testosterone before but it made them worse it seems.

They also said other DHT products like DHT cream and proviron didn't help, only DHB did.


And also happy Kikel will still be giving these updates about PFS since he also had to deal with drama because his coaching is so expensive.

Alex Kikel on Instagram: "I know I said I was going to stop posting free Post Finasteride Syndrome related content but after a week of having so many people in the community reach out and tell me how much this content has helped them, I truly do feel

209 likes, 13 comments - alex_kikel on May 2, 2024: "I know I said I was going to stop posting free Post Finasteride Syndrome related content but after a week of having so many people in the community reach out and tell me how much this content has helped them, I truly do feel obligated to help...

www.instagram.com

 

[Mister]

New PFS recovery with HCG:


View: https://www.reddit.com/r/FinasterideSyndrome/comments/1cnct77/pfs_recovery_after_15_years/


Also interesting video from Kikel about the androgen receptors:


View: https://vimeo.com/944135442


Things he mentions to improve the AR: More muscle mass, more androgens (TRT, dht derivatives), boron, injectable carnitine,...

 

[Mister]

New Lion's mane recovery from Kikel.

Alex Kikel on Instagram: "CLIENT CASE STUDY: POST LIONS MANE REVERSAL This was an extremely interesting case to discuss for a few reasons and so I wanted to break it down to help people out as we tend to classify all of these accutane, SSRI, lions ma

166 likes, 18 comments - alex_kikel on May 13, 2024: "CLIENT CASE STUDY: POST LIONS MANE REVERSAL This was an extremely interesting case to discuss for a few reasons and so I wanted to break it down to help people out as we tend to classify all of these accutane, SSRI, lions mane, finasteride...

www.instagram.com

Guy got some improvements from trying all kinds of herbs first but needed things like DHT, HCG, etc to get to an almost full recovery.

Also interesting new article on secondlife:

Restoring 5-alpha-reductase: Epigenetic Modification - SecondLife

5-alpha-reductase Finasteride is a commonly used medication for treating androgen driven conditions such as male pattern baldness or benign prostatic hyperplasia. It inhibits the activity of the type II 5-alpha-reductase enzyme, which converts testosterone into the much more potent androgen...

secondlifeguide.com

 

[fever257]

I want to share an updated experience of a PFS sufferer.

I’m still struggling 5 years after coming off of finasteride, though I have gotten much better.

I’m doing better now with a higher thyroid dosage and topical test base @ 10mg per day.

The TRT, strangely, stops my worst symptoms - extreme depression, suicidal ideations, brain fog, consistent dissociations, extreme IBS (like ~15 diarrhea BMs per day), weird aches & pains, etc. I’ve tried to come off of it but I just can’t right now.

The higher thyroid dose is over 2 grains now. I’m trying to support my liver. I think most of my problems are due to poor liver function and lack of bile flow. I’m hoping this will improve over time now that my thyroid dose is higher but I doubt it. Any other PFS sufferers think their liver is the main issue?

I’m obviously very estrogenic in general too tho.

 

[Mister]

I want to share an updated experience of a PFS sufferer.

I’m still struggling 5 years after coming off of finasteride, though I have gotten much better.

I’m doing better now with a higher thyroid dosage and topical test base @ 10mg per day.

The TRT, strangely, stops my worst symptoms - extreme depression, suicidal ideations, brain fog, consistent dissociations, extreme IBS (like ~15 diarrhea BMs per day), weird aches & pains, etc. I’ve tried to come off of it but I just can’t right now.

The higher thyroid dose is over 2 grains now. I’m trying to support my liver. I think most of my problems are due to poor liver function and lack of bile flow. I’m hoping this will improve over time now that my thyroid dose is higher but I doubt it. Any other PFS sufferers think their liver is the main issue?

I’m obviously very estrogenic in general too tho.

If you're estrogenic maybe add DIM or low dose AI? Adding a DHT could help too.

And on that note new post from Kikel confirming what I already thought. But for some even DHT/DHB won't be enough and a HDACI will be necessary imo.

Alex Kikel on Instagram: "Although people can recover naturally, it is the minority (but obviously depends on the extent of your dysfunction.) #theprepcoach"

137 likes, 17 comments - alex_kikel on May 24, 2024: "Although people can recover naturally, it is the minority (but obviously depends on the extent of your dysfunction.) #theprepcoach".

www.instagram.com

I'm also in contact with a guy from reddit that's bascially 99% recovered thanks to TRT, HCG and taking a bunch of DHT steroids together like primo, proviron, etc. And he also took and still takes sulforaphane at 300mg/day (hdaci as strong as vorinostat according to a study). He also tried lithium and sodium butyrate but got bad effects from those.