The Molecular Therapy of William Frederick Koch
by Dr. Carl Windstosser, Bircher-Benner Klinik, Switzerland
[ Translated by Clifford Myles ]
Summary:
All physiological and pathological metabolic processes originate in atomic and molecular levels. A fundamental role in this case are the free radicals. These are highly reactive, usually short-lived activated carbonyl groups that are primarily life supporting, but can also occur as a hostile function. As an orthomolecular, a free radical has the carbonyl group> C = 0 as cell respiration. If this combination, through nitrogen admission becomes toxic azomethine> C = N --C--, this can lead to the disorder of mesenchymal basic regulation and thus the intermediary metabolism and cellular respiration. It then comes to the loss of the genetic reparative and immunocompetent capabilities of the organism to life-threatening infections and chronic degenerative ailments and to malignancies. For the formation of azomethine the unnatural foods, nutritional and environmental conditions contribute continuously and to an increasing extent.
William Frederick Koch succeeded to break the toxic free radicals with partly cyclical, partly aliphatic structured carbonyl high oxido-redox potential and thus to eliminate the pathogenic blockages, due to his profound biochemical knowledge and resources. The preparations, their indications and methods of use as well as the complementary protien restrictive diet are explained below.
Under all totalitarian and systemically oriented tumor treatments, the latest and perhaps most promising method is based on the findings of the products derived from molecular biology emerging as electron transport biology (Szent-Györgyi, Együd, Greenberg, Appel et al).
According to Koch the carbonyl C = O are the main functional units of the
molecular level of biological events. Their double bond and the
double bonds of similar molecular structures are the key players of electron dynamics. The electron movements are ultimately the metabolism, that is the energy absorption, distribution and emission in the context of specific cellular functions. Civilization’s damaging effects such as malnutrition, endogenous and exogenous toxins, also of bacterial origin, radiation effects, also geopathic effects, drugs, carcinogens and many other factors lead to the blockage of the carbonyl functional groups and hence the disease process in general, and the cancer-specific cell respiration disorder in particular.
The most widespread and dangerous disruptive factor accordeing to Koch is the development by alien amino particle displacement of the oxygen atom of the
C = O bond and converting introduced nitrogen to C = N-N. This highly toxic azomethine group is particularly stable and can be reconverted only through the use of more powerful catalysts with higher redox potential. Such substances were found by Koch in para-benzoquinone and glyoxal and derivatives thereof. The technically, very complicated production of these preparations were carried out by Fa. Roedler in 6521 Florsheim (Germany). Their successful application depends on instruction and fundamentals on the part of the practitioner, and willingness for the patient to go on a vegan diet in advance. Since the presence of animal protein the body, even in trace amounts, nullifies the molecular therapeutic effect, the patient must abstain from consuming meat, fish, eggs and milk in any form.
Most representatives of holistic medical tumor therapy endorse the requirements of a lacto-vegetarian diet but Koch's treatment required an entirely new, especially psychologically difficult to master situation for all concerned. The protein requirements in (Koch’s therapy) can only be supplied with plant products. Physiologically this is less problematic when we consider that each leaf, each grain, paticularly legumes (soy), almonds, nuts and mushrooms are protein carriers, also, that the actual protein requirements of an adult with an otherwise high-quality, vitality-rich diet is far below the requirements of an outdated, outmoded Nutrition level.
The recent publications of Prof. Wendt (Frankfurt), recalls, the report on the inclusion of all qualitative and quantitative incompatible proteids as amyloid in the capillary wall with all its consequences for cellular metabolism, further to the studies of Dr. Aschoff (Wuppertal), about the exact proportionality between the protein content of the milk and the doubling time of the weight of the thus-fed newborns, a process which takes place exactly species-specific. Example: Human breast milk = 1.3% protein, by weight doubling in 180 days; Cow's milk = 3.7% protein, by weight doubling in 47 days; Rabbit milk = 10.4% protein, by weight doubling in 6 days. If the milk as the exclusive food of the newborn is inherent in such a growth-enhancing force, the question arises whether in the adult, this tendency could impact toward tumor growth.
Experience with the therapeutic use of free radicals are not yet available to a significant extent from these two researchers. From various other sources (Reinstorff, Plohberger, Draczynski, Doerfler, Kempe, Gleichmann et al) there is materiel with reference to smaller case reports of sensational successes. In addition, reference is made to the published in Haug-Verlag original work of Koch: “The Survival Factor in Neoplastic and Viral Diseases – Key principles of cure”, (German translation, edited by Dr. Erich Reinstorff (†) ).
For therapeutic use of free radicals, it should also be noted that their injection
both i.m. and i.v. can take place, however, to avoid magnetic and other interferences, a strong calibrated, pre-rinsed, absolutely dry needle should be used according to manufacturers instructions. Since the preparations are not isotonic (they are manufactured using specially prepared water, but without the use of physiological NaCl solution) and given a thick cannula i.m.- injections are quite painful, which does not apply to i.v. administration. Hemolytic side effect is not to be feared for the small amount of the injected preparation. The patient having been placed on the preparatory diet in advance recieves a selected radical generally only once. Its effect is catalytically comparable by the starter motor of an engine that needs no further starting assistance after it is running. The reconversion of pathologically blocked carbonyl is in compliance with the mentioned medicinally diet and other requirements like a chain reaction going on. All other forms of interfering therapy should be witheld during this period.
Medical research and therapy moves its focus more and more from the morphological phenomena of the cell and its components to the energetic processes in the molecular and atomic levels. This approach has much to offer with today's possibilities and can be recognized and predicted to improve areas of human life in substantial ways.
Moses Gomberg (USA) was one of the first to deal with the phenomenon of free radicals in organic chemistry at the turn of the century. This research continued with his pupil William Frederick Koch (1885-1967). As a doctor in the medical field, he continued and extended the principles to their therapeutic practical applications. After several important scientific publications Koch completed in his standard work "Survival Factor in Cancer and Viral Diseases, The Key Principle of their Curability,” in 1955. It also appeared in 1966 as the German translation by Erich Reinstorff [7]. The subtitle reads: "A study of the phenomenology of free radicals, the double bonds and its contained alpha-hydrogen atom in the pathogenesis and treatment of neoplastic viral and bacterial disease" This publication was a "preliminary report" in 1919 with the title "A New and Successful Treatment of Cancer", published in "Detroit Medical Journal". In it and in the following documents all options and methods of prevention, the arrest and regression of degenerative cellular changes were countered fully described and justified, according to the Warburg thesis of irreversibility of cancer. Due to numerous well documented sucessful medical cases, this new doctrine was demonstrated.
W. F. Koch initially worked as a teacher of biology, embryology, physiology and
Pathology at various medical colleges in Michigan (USA), particularly in Detroit. As he demonstrated repeatedly his sensational successes in drug-resistant diseases with his novel mode of treatments, such as cancer, multiple sclerosis, viral infections, poliornyelitic paralysis, advanced tuberculosis, severe cases of allergy, etc. As a result, the usual attacks, slander and suits from orthodox medicine were not witheld. Koch moved his activity as a physician and researcher then to Rio de Janeiro, where, together with his team, he scored thousands of improvements and cures in these and similar illnesses in a private, independent university cancer clinic 1919-1949. Encouraged and supported by open-minded doctors led Koch to bring his method to Europe . In 1965 he instituted in collaboration with Erich Reinstorff (Hamburg, Germany) the "Research Group for Molecular Therapy by Prof Dr. Dr. William Frederick Koch e.V.".
{ Translators note: Dr. Erich Reinstorff’s son, Dr. Dieter Reinstorff continued this Research Group until the latter’s death in 2014. }
Koch’s molecular therapy requires a high level of cooperation of the patient, patience from both sides and the expert knowledge of the practitioner. For this reason alone, not because of any risk, it is not routinely used as some other therapy. Often they must be stopped halfway due to erroneous behavior of the patient. Most often this relates to serious breaching of the nutritional principles that always make continued treatment problematic. If however there are reasons, one should definitely try to convince the patient of this therapy. It is particularly good as a prelude and first action before the transition to other biological or even conventional forms of treatment of oncology. However, it must be remembered that the priority of infection foci elimination, the removal of geopathic influences and nutritional modification is of utmost importance.
Prepared and carried out in this way, molecular therapy can have highly beneficial effects. But, it is not the “philosopher's stone”. The underlying principle of non-toxic and residue-free recovery by metabolic catalysts that remain as endogenous metabolic and undetectable by their task that continue to work, is a principle that could initiate a new era of non-violent integrative medicine.
The starting point of the molecular therapy is the effect of the above-mentioned free radicals in the metabolism. These are groups of atoms or molecular fragments of exogenous or endogenous origin with specific biochemical function, which can be both vital and hostile. They differ, due to the presence of a single unpaired electron, of other atomic groups in terms of their paramagnetic properties, which prevents them to submit to the nuclear spin orientation. Because of their high reactivity, free radicals have short life. During this time they catalytically resolve harmful metabolic processes much like a chain reaction might function.
There are countless types of free radicals one of which is atomic oxygen, but not singlet oxygen and ozone. In healthy persons they outweigh the metabolic, orthomolecular, life sustaining radicals. The possible presence of harmful radicals in the sense of homeostasis and steady mesenchymal matrix regulation are eliminated as they arise. This is done by means of the factors of an intact enzyme system such as superoxide dismutase, catalase, glutathione peroxidase, etc. A healthy metabolism can cope in this way with a certain amount of temporarily occurring toxic radicals. However, if damage of this ability occurs as it does with most residents of industrialized countries, it comes to the accumulation of such free radicals with all its sequelae. The people of the western world are continually exposed to a prevailing unbiological lifestyle and nutritional conditions creating countless occasions for forming or receiving free radicals with a negative result.
Civilization’s damage, environmental toxins, endogenous and exogenous noxious agents, ionizing radiation, electromagnetic and geopathic fields, permanent stress, para moleculelar drugs, toxins from tobacco and alcohol, and especially the lifelong effect of a loss of instinct that becomes denatured, the industrially manipulated and media steered diet leads to blockages of the essential molecular reaction and thus to uninhibited proliferation of toxic radicals with its sequelae. These increasingly hinder the interaction of many other maintaining and sustaining fundamental life functions, the coherance of the respiratory chain and consequently the oxygen utilization and detoxification processes, the photoassimilation, incorporation of highly unsaturated fatty acids in the cell membrane, and the intercellular and genetic information. In short, it results in the first local, later the general failure of the mesenchymal regulatory processes up to the formation of the first tumor cell.
The active orthomolecular carbonyl > C = 0 is the most important of all free radicals within the essential biochemical processes. The reversible double bond between carbon and oxygen is this radical protagonist of the electron dynamics. This maintains and regulates the whole metabolism, as well as all energy conversion processes and cellular functions
For Koch, the most widespread and dangerous disruptive factor of energy balance is overloading with nitrogen - rising from amino acids or alkylating agents, resulting in the displacement of the oxygen atom from the bond > C = 0 through N and the change to > C = N -C--. These non-physiological "azomethines" are highly toxic, and, unlike most free radicals stable and durable. They are deleterious in their purpose to the mentioned enzyme blockages and other dysregulation.
The azomethine groups can only be reconverted to stronger energy and higher redox potential> C = 0th through catalysts. This simultaneously manages the
regression and reintegration of malignant cells, highly toxic viruses and other
pathogens in the normal tissue metabolism. Koch availed himself of the derivatives he developed, that were compatible without secondary damage or side effects:
1.) The cyclic molecules of para-benzoquinone and rhodizonic acid
with 2 or 4 carbonyl groups
2.) The cyclic Trichinoyls with 6 carbonyl groups
3.) Allopathic molecules of (endogenous) glyoxal and methylglyoxal
with 2 carbonyl groups
4.) The allopathic polyketones having 2-10 carbonyl groups (trade name
"Carbonyl group comp. SSR").
Prerequisite for the optimal effect of molecular therapy is the elimination of the
main sources of toxic compounds. This is only possible by switching to a
diet that dispenses with any kind of animal protein at least 3-6 months.
This corresponds exactly with the recommended protein restriction in the treatment of medical conditions as "hyperproteinemia" by Wendt, described by him, and "hypoporopathy" [lowered permeability of capillary membranes due to thickening](18-20). We call this form of vegetarianism as "Vegan food". Not only meat, sausage, fish and all marine animals, but also milk and all dairy products such as buttermilk, yogurt, cottage cheese and cheese of any kind and eggs.
It has been proven and exemplified often by supporters of veganism for decades that such a diet can be consumed by people of all ages on a permanent basis.
It prevents iron deficiency by eating leafy vegetables, fruits and whole grains, containing all the vitamins and trace elements, even the frequently cited B12 deficiency can be compensated by parsley and other herbs, as well as a full intestinal flora. Anyone, but at least lacto-vegetarians nourished by vegan principles, are freed through the benefits of the orthomolecularity of the resulting endemic acidification as an expression of the acid-base dysfunction, which in turn has to be considered as cause and regulator of many deposition and inflammatory diseases (anti -acid-Diet). Acidosis descends with the removal of pathogenic tissue and at the same time their reciprocally proportional, cancer-beneficial alkalosis of the blood [21].
In hyperproteinemia, enteral incurred co-carcinogens are always present, detectable in urine and blood as decay products indole, urorosein, cadaverine and putrescine which are thereby reduced. Some components of "whole foods", for example vitamin C, glutathione, selenium etc. are defined directly as "free radical scavengers".
During and after Koch molecular therapy, animal protein must not be given for a period of several months in any form, - no meat, no fish, no dairy products and eggs. The protein requirements must be met during this time exclusively by vegetable protein: whole grains, legumes, nuts, almonds, soy products, also glidine (grain protein), (chewed nuts and almonds are digested insufficiently and the use of nut and almond butters is recommended). The reason for this drastic ban is that KOCH indicates that animal protein (postmortem or extracorporeally) forms toxic amines rapidly (which also arises in a dysbacterial intestinal flora milieu). These amines cause and maintain the blockade of the carbonyl groups in the cancer tissue, their removal is the goal of Koch's therapy. Any food tha is different from that described here is not recommended.
Above and beyond it’s therapeutic benefits, vegetarianism, as well as veganism, have indefinite broad-based economic, ecological and economic advantages over conventional economic and supply systems by reducing the need for extensive forage crops, the preservation of biological balance and the direct delivery to humanity with vegetables, grains and fruit. There is sufficient evidence of this in the form of experience in regionally limited areas.
Such animal proteins and albumin-free food can be quite delicious and satisfying and varied. This is described in the kitchen-oriented book of Helga Leyk [8], aimed specifically at the Koch molecular therapy.
Since the presence of azomethine groups contained in animal protein, even in small amounts, the conversion of
> C = N -C-- to> C = 0
is made difficult, impedes and impairs molecular therapy or renders it completely
ineffective, the patient on the vegan diet must start it at least 14 days before the
first Carbonyl group injections begin, strictly continuing thereafter depending on the type and severity of the disease, and in accordance with future necessary
repeated injections, if any, for several months, or even years. The opportunity associated with good health with greater security and to remain so, is to certainly facilitated in this change in lifestyle.
Immediately preceding the Koch therapy there are few fasting days on which you should drink only distilled water, unsweetened herbal tea, sugar-free fruit or vegetable juice, vegetable broth. Prolonged fasting is indeed the "royal" road to profound healing process from the inside out, also it is the best way to quick deacidification.
The injection technique should be administered as recommended by the manufacturer of the preparations. The homeopathic substances contained in the ampoules are as sensitive as the radicals. The are produced in a complex process without the use of salines, thus not isotonic, therefore subcutaneous or intramuscular injection is extremely painful. It is given intravenously without complications, - a little autologous blood can be drawn and mixed with the ampoule contents within the syringe. When mixed with 3-5 ml of blood, the injection also succeeds i.m. without pain with the advantage of autohemotherapy.
A large diameter, short cannula (1.2 x 30 mm) as used for drawing blood is employed to allow the liquid to contact the metal for as short a time as possible.
Because traces of metal dust can make the means ineffective inside the needle, the plastic or all-glass syringe is first repeatedly flushed with the needle with sterile aqua
not saline, then filled from the ampoule. It is then injected as quickly as possible with or without autologous blood, for that reason. Any unpleasant reactions are not to be feared, apart from very rare allergies to para-group compounds.
For children, preparations in vials are used. Orally given, carbonyl can also cause notable improvements including energy balance and the subjective condition. This form of therapy is also recommended as a maintenance dose with appropriate intervals after completion of the initial injections in adults. There is also a topically and orally usable carbonyl-aerosol with glyoxal and methylglyoxal in an alcohol solution, supportive for daily use.
The catalytic effect of carbonyl, as well as the toxic free radicals run as a chain reaction. The injections: - one recalls the principles of homeopathy and to the “actuation of a starter motor in a car - not too early and not too often repeated.
In oncological diseases the rule is every 7-14 days. This does not apply to oral doses. In zoster with herpes (and some other acute illnesses) two daily injections are recommended daily. Here also, the diet principle of immediate rigorous and multi-day fasting taking place during preparatory days. The treatment intervals are directed by the reactions and the condition of the patient and according to the course of the tumor affection. Impending improvement or remissions are not to be disturbed by premature or even para molecular measures. Even with the methods of holistic therapy, application of the carbonyl groups should be restrained, so also with mistletoe preparations, electrolytes and enzymes.
Strictly to be avoided are all drugs, cytostatics, radiation, anesthesia, surgery and rehabilitative measures because they thwart the molecular reaction. These must also have been completed at least 4-6 weeks in advance of therapy and may not continue after therapeutic success is achieved or repeated application. When it becomes necessary to relieve pain relief opioldes are preferred, as well as neural therapy and acupuncture.
An exception to the mentioned incompatibilities are oxygen and ozone. These are useful to restore cellular respiratory gases and are even desirable because the parenterally given carbonyl in quinone form together with O2 and O3 in cancer cells of accumulated hydroquinone to oxidize quinone or substitute the blocked normal cells’ quinone. This is the most important for the cellular respiration member of the respiratory chain as a condition for switching from the proton to electron transport. The intact respiratory chain in turn forms the basis of the interaction of all vital control loops and thus any immunity and order function.
As a standard for O2O3-supply, 600-1200 μg per week, divided into 2-3 doses per 20-60 μg 03 / ml application IM without autologous blood, with autologous blood (HOT) IV, alternatively, with oxygen inhalation 1 to 3 times weekly for 15 minutes at 4 l O2 / min flow preferably using pulse-matched load with 20-150 W. (long-term program of classical KMT according to v. Ardenne).
Notable improvements and cures in mainly chronic diseases such as multiple sclerosis, scleroderma, PCP, eczema, diabetes, cerebral sclerosis, autoimmune diseases, hepatitis, herpes zoster, etc., in which therapeutic alternatives are hardly available, especially malignancies of all organ areas and severities including lymphomas and leukemia, are detailed in publications [3,6,7].
Koch’s therapy applies especially to Dieter Reinstorff [10, 11], who published a new version of Koch's standard work in a 2nd edition (in German). His results were further confirmed by Dr. Windstosser for 15 years in the exclusive oncological care of more than 4,000 cancer patients and cancer at risk. Koch and his staff in a sensational FDA trial, documented 20,000 successfully treated patients in the US.
The preparations are produced according to Koch’s original method manufactured by pharmaceutical Biologica-Tonia GmbH, Flörsheim-Dalsheim. Consultations and information provided in therapeutic issues are also available from the office of the Research Group, Dr. Dieter Reinstorff, Bruno-LauenrothWeg 31, 22417 Hamburg, Tel .: 040/5 20 25 02, Fax: 040/5 20 33 10)
[Translators note: Dr. Dieter Reinstorff passed away in 2014, his office is closed]
1. Rhodizonic acid comp. N-ampoules
Content: Rhodizonic acid, Trichinoyl and Glyoxal equally into each D 6 (this number indicates the degree of dilution, however, has nothing to do with the principle of the manufacturing process of homeopathic remedies).
Indications: Acute and chronic viral infections, diseases and late complications of the liver, lungs and kidneys, connective tissue diseases, dermatosis, nervous diseases, pre- and postoperatively in all tumor diseases alternating with carbonyl comp. SSR ampoules. Application: each 1 Amp all 2-14 days.
2. Carbonyl group comp. SSR ampoules
Content: carbonyl polyketone in D6.
Indication: As in 1, especially with herpes zoster. Pre- and postoperatively in all
Tumor diseases, alternating with 1: As with. 1
3. Carbonyl group ampoules
Content: glyoxal and methylglyoxal equal parts in each D6.
Indication: As in 1 and 2, especially in breast, uterine, stomach and intestinal cancer. Application: As in 1
References:
(1) Butenandt, A.: Molekulare Biologie als Fundament der modernen Medizin. Münchner
Med. Wschr. 34 (1966).
[2] Floyd, R.A.: Free Radicals and Cancer. M. Dekker Inc., New York 1982.
(3) Grabowski, S.: Grundlagen der Therapie mit Elektronendonatoren und Radikalenfängern. Eigenverlag, Berlin.
[4] Guillot, B.; Despages, G.: Les radicaux libres a la racine des pathologiques. De natura
rerum 2 (1988) 52-58.
[5] Hartweger, E. W S.; Reinstorff, D.: Erfahrungen mit der Molekulartherapie nach Professor Koch, insbesondere im Hinblick auf die Tumortherapie und die Kombination mit anderen nichttoxischen Therapieformen. Das Seminar 3 (1983).
[6] Hentze, M. W; Kulozik, A.E.; Bartram, C.R.: Einführung in die medizinische
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[14] Reinstorff, E.: Die Molekulartherapie von Prof. Dr. Dr. William Frederick Koch und der sogenannte "Koch-Effekt". Erfahrungsheilkunde 16 (1967) 301306.
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(23) Wendt, L.: Krankheiten verminderter Kapillarmembran-Permeabilität. Verlag E. E.
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[24] Wendt, L.: Ist eine vorwiegende Fleischkost gesundheitsschädlich? Med. Welt. 11(1977).
[25] Wendt, L.; Petri, S.: Eiweißfasten. Rezepte für die Eiweiß-Abbaudiät. Karl F. Haug
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Krebsgeschehens. Vortrag gehalten auf der Med. Woche Baden-Baden 1992.
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