Amazoniac
Member
It's surprising how little discussion there is on this topic. The influence must occur both ways. I don't have it clear yet but hopefully this thread encourages investigation on their interaction and balance.
- https://www.westonaprice.org/health...a-on-trial-does-vitamin-a-cause-osteoporosis/
- Effects and Interactions of Dietary Levels of Vitamins A and E and Cholecalciferol in Broiler Chickens
- https://raypeatforum.com/community/...erves-of-the-liver-may-be-much-reduced.16124/
Time to search for excess vitamin E and signs of vitamin A deficiency..
All life matters.
- https://www.westonaprice.org/health...a-on-trial-does-vitamin-a-cause-osteoporosis/
"Several studies, when taken together, suggest that vitamin E can interfere with the functioning of, or increase the need for, vitamin A. In Nutrition and Physical Degeneration, Weston Price described the importance of vitamin A for the development of eye tissue and cited experiments carried out by Fred Hale, wherein vitamin A-deficient pigs gave birth to offspring with a variety of eye defects, including blindness and in some cases the absence of eyeballs.43 In a more recent study,44 researchers injected the environmental pollutant TCDD, the most potent dioxin, vitamin E as a-tocopherol succinate, and vitamin A as retinol acetate, into eggs containing chicken embryos, and then let the chicks hatch. Vitamin A and vitamin E both protected against TCDD-induced birth defects, but vitamin E caused birth defects of its own – mostly eye abnormalities. One chick, like some of Fred Hale’s vitamin A-deficient pigs, was even born with no eyes.
TCDD, which acts as a hormone and both mimics vitamin A and opposes vitamin A in various ways,45 helped reduce the vitamin E-induced birth defects, but the researchers did not test whether or not vitamin A protected against these birth defects. In humans, vitamin A helps improve the eye disease retinitis pigmentosis, while vitamin E accelerates it.46 If high doses of vitamin E can induce the same eye defects as induced by deficient doses of vitamin A, and if vitamin E accelerates the same eye diseases as are helped by vitamin A, then vitamin E’s toxic effects on the eye may result from a depletion of vitamin A. In fact, excessive doses of the a-tocopherol form of vitamin E not only interfere with the functioning of vitamin A, but actually interfere with the functioning of vitamin E itself, by inhibiting the action of the other important parts of the vitamin E complex.47"
[47] Dommisse, John, “B12: Difficulties and Obstacles in Diagnosing and Treating B12 Deficiency,” Wise Traditions 2005, November 12, 2005.
TCDD, which acts as a hormone and both mimics vitamin A and opposes vitamin A in various ways,45 helped reduce the vitamin E-induced birth defects, but the researchers did not test whether or not vitamin A protected against these birth defects. In humans, vitamin A helps improve the eye disease retinitis pigmentosis, while vitamin E accelerates it.46 If high doses of vitamin E can induce the same eye defects as induced by deficient doses of vitamin A, and if vitamin E accelerates the same eye diseases as are helped by vitamin A, then vitamin E’s toxic effects on the eye may result from a depletion of vitamin A. In fact, excessive doses of the a-tocopherol form of vitamin E not only interfere with the functioning of vitamin A, but actually interfere with the functioning of vitamin E itself, by inhibiting the action of the other important parts of the vitamin E complex.47"
[47] Dommisse, John, “B12: Difficulties and Obstacles in Diagnosing and Treating B12 Deficiency,” Wise Traditions 2005, November 12, 2005.
- Effects and Interactions of Dietary Levels of Vitamins A and E and Cholecalciferol in Broiler Chickens
"Studies have demonstrated that the feeding of high dietary levels of vitamin A leads to decreased tissue and plasma tocopherol concentrations in chicks (Pudelkiewiczet al., 1964; Combs and Scott, 1974; Combs, 1976; Sklan and Donoghue, 1982; Frigg and Broz, 1984; Abawi and Sullivan, 1989). Conversely, high dietary tocopherol alleviated hypervitaminosis A in chicks (McCuaig and Motzok, 1970; Sklan and Donoghue, 1982)."
"March et al. (1973) reported that with calcium- or vitamin D-deficient diets, bone calcification was depressed when chicks were given excess vitamin E. Similarly, Murphy et al. (1981) observed reduced bone ash and plasma calcium and phosphorus when chicks were given large doses of vitamin E. A significant three-way interaction among vitamins A, D3, and E was noted for plasma vitamin E concentrations in broiler chickens (Abawi and Sullivan, 1989)."
"Although it was not a major objective of these studies to look at the dietary interactions of vitamin A and vitamin E it was clear from the blood levels in Experiment 4 that this relationship does exist. Feeding excess vitamin A decreases the blood and liver levels of vitamin E and feeding excess vitamin E decreases the blood and liver levels of vitamin A. The mechanism of this relationship needs further study."
"March et al. (1973) reported that with calcium- or vitamin D-deficient diets, bone calcification was depressed when chicks were given excess vitamin E. Similarly, Murphy et al. (1981) observed reduced bone ash and plasma calcium and phosphorus when chicks were given large doses of vitamin E. A significant three-way interaction among vitamins A, D3, and E was noted for plasma vitamin E concentrations in broiler chickens (Abawi and Sullivan, 1989)."
"Although it was not a major objective of these studies to look at the dietary interactions of vitamin A and vitamin E it was clear from the blood levels in Experiment 4 that this relationship does exist. Feeding excess vitamin A decreases the blood and liver levels of vitamin E and feeding excess vitamin E decreases the blood and liver levels of vitamin A. The mechanism of this relationship needs further study."
- https://raypeatforum.com/community/...erves-of-the-liver-may-be-much-reduced.16124/
Time to search for excess vitamin E and signs of vitamin A deficiency..
All life matters.
Last edited: