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klotho

  1. Mauritio

    T3 increases klotho, reduces lipofuscin and oxidative stress

    Most people probably heard of the gene klotho by now. Overexpression of klotho in mice leads to an increase in health and life expectancy. Peat has also spoken favorably about it : View: https://www.youtube.com/watch?v=OBKyKFCN_2E I have previously posted about anti-aging benefits of T3 : -...
  2. Limon9

    Endotoxin (LPS) suppresses "anti-aging protein" Klotho

    Molecular cloning of rat klotho cDNA: markedly decreased expression of klotho by acute inflammatory stress Biochem Biophys Res Commun. 1998 Oct 29;251(3):920-5. Ohyama Y et al. "We have recently identified a novel gene, termed klotho, that is involved in the suppression of several aging...
  3. Mito

    The Metabolic, Neuroprotective Cardioprotective And Antitumor Effects Of The Klotho Protein

    Abstract Klotho is a transmembrane protein with a wide spectrum of activity. The human Klotho gene shows 86% amino acid identity with the mouse protein. Many important pleiotropic functions of the Klotho protein have been revealed. Amongst them, there is a regulation of nitric oxide production...
  4. haidut

    Policosanol Is Antiviral And A Potent Inducer Of Anti-aging Gene Klotho

    This post is a good complement to the recent ones I did on androgens, estrogens and their opposing effects on the expression of the anti-aging gene Klotho. While I was doing research on that gene, I had a "random" thought pop up in my mind. It is well-known that some Caribbean countries have a...
  5. haidut

    Androgens Boost, Estrogen Inhibits, Anti-aging Gene Klotho

    This post has two main messages, based on the studies below. Namely, androgens (and especially DHT) potently increase the expression of the anti-aging gene Klotho while estrogens strikingly decrease its expression. Moreover, the more potent the androgen, in terms of androgen receptor (AR)...
  6. H

    The Anti-aging Protein Klotho Induced By Gaba

    The anti-aging protein Klotho is induced by GABA therapy and exerts protective and stimulatory effects on pancreatic beta cells. - PubMed - NCBI The anti-aging protein Klotho is induced by GABA therapy and exerts protective and stimulatory effects on pancreatic beta cells. Prud'homme GJ, et...
  7. haidut

    Calcirol - Liquid Vitamin D3

    Just like the other vitamin products we have released, this product does not really need any introduction to anybody familiar with Peat's work. So, unlike other products of ours, there won't be as many references listed in support of this product but I think even the few ones below are enough to...
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